Wednesday, October 20, 2010

Ipilimumab - Take Two

I've now received my second dose of ipilimumab and so far so good. Just like everyone else that I've spoken to who are receiving the drug, we are all handling the early treatments with little to no effects. Once again after this dose, I feel fine. I continue to have a huge appetite, sleep well and have all my energy. 

Over the past three weeks I've changed things up quite a bit. I'm now eating a wider range of fruits and vegetables and I've introduced some bread and a little cheese into my diet. It has been an exciting time around the house recently as we are once again planning and preparing meals for the week ahead. Now that I am getting a wider variety of foods I have noticed that the joint pain in my wrist has gone away. I'm also up about 10 pounds and holding steady at around 150.

One interesting thing to note from yesterdays appointment was from my blood work results. As I've been reporting for sometime my LDH has been on a slow and steady rise. That momentum has finally changed and for the first time it has actually dropped. It was down about a 100 points from where we were just three weeks prior. Though Dr Spira suggests that this is nothing to get too excited about because it could be a chemo-reactive response. We both agreed that a down response is much better than up.

In the next few weeks I'll be working with my doctors to get on the list to receive Zometa to shore up my leg while I await my durable complete response from ipilimumab. This will be another infusion that will be administered every month while I need it.

I am now working outside of the house twice per week. I've truly been lucky to have such great business partners and an understanding customer while spending the last year dealing with this crap. We are only a few months away and I should be good as new. Like a fine wine, I'll return aged and sport that vintage look with my white hair.


Anonymous said...

I'm so glad! thumbs up....we'll just call you Einstein sipping wine....cindy

smitty240 said...

Glad things are going well. I received my 3rd dose today in CLT. Drove home afterward, no problems. Hope you continue side effect free. Your spirits are great, that's half (95%?) of the battle. Keep posting, we're pullin' for you.

Lynn said...

Happy you are doing Ipi. On IPI it is expected that before they shrink they may grow so don't get discouraged! I believe a healthy diet is important. I do a lot of suppliments as well. I am in a vaccine trial at Moffitt using MDX 1106 (anti PD-1)and protein/peptides. My LDH is 382 UL and went up to 502 UL after the first dose...usually it sits at or below the bottom of normal values.I am Stage 4 Melanoma NED.- Lynn L

Laurie said...

So good to hear from you, Mike! You've been on my mind continuously...and I've checked back often for an update. Sounds like life is getting a little more "normal" (stupid word, but couldn't come up with a better one). :o)

So how was that piece of birthday cake? Don't I recall you saying you were going to have a blue cupcake or something??? I'm all about the treats!

Good news, is good a reduced LDH deserves a big WOO HOO!!!

Love and prayers to you and all the other Brockey's in your house! Miss you oh-so-much!!!

<3 Laurie

Anonymous said...

I had been arguing with my close friend on this issue for quite a while, base on your ideas prove that I am right, let me show him your webpage then I am sure it must make him buy me a drink, lol, thanks.

- Kris

Anonymous said...

thank you for your updates...
I've been checking in with this blog for the past year, since my mom was diagnosed with brain cancer.
For a time, she was considering Gerson... hence I discovered this blog, but I still come back to find encouragement when I'm down.
I really admire your attitude and your drive to live. Thanks for showing how important it is to evaluate your treatment and, if it's not working, to change course. It's so easy to lose hope when things don't look good. Your optimism is such a boost to all of us.

Wishing you much health and happiness to come,